A detailed molecular diagram illustrating the electron transport chain in a mitochondrion, leading to ROS production and activation of various cellular pathways like autophagy and caspase cascade.
็บฟ็ฒไฝ็ตๅญไผ ้้พ (ETC)๏ผๅๅฐ FADH2 ็ตๅญไพ็ป๏ผๅฏผ่ด็ตๅญๆณๆผ๏ผ็ตๅญๆณๆผไบง็่ถ ๆฐง้ด็ฆปๅญ็ญๆดปๆงๆฐง (ROS)๏ผROS ้่ฟๆๅถ MAPK ็ฃท้ ธ้ ถ (MKPs) ๅ็ดๆฅๆฟๆดป ASK1๏ผASK1 ่ฟ่ๆฟๆดป JNK ๅ p38 MAPK ้่ทฏ๏ผJNK ๅ p38 ็ฃท้ ธๅ Bcl-2๏ผไฝฟๅ ถไธ่ฝๆๅถ Beclin-1๏ผ้ๆพ Beclin-1 ๅฏๅจ่ชๅฌ๏ผๅๆถ่งฃ้คๅฏน Bax ่็ฝ็ๆๅถไฝ็จ๏ผ้ๆพ็ป่่ฒ็ด c๏ผๆฟๆดป caspase ็บง่ๅๅบ๏ผๅฏผ่ดๅฟ่็ป่ๅไบก Voir plus
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