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An educational illustration of a human HeLa cell with labeled organelles and proteins, showing apoptotic priming pathways blocked by HPV.

An educational illustration of a human HeLa cell with labeled organelles and proteins, showing apoptotic priming pathways blocked by HPV.

A stylised, educational illustration of a single human HeLa cell, shown as a cut‑away diagram with visible organelles. The cell is on a white background, drawn in a clean vector‑style. The overall theme is "Apoptotic Priming blocked by HPV E6/E7". Inside the cell, label the following organelles clearly: - Nucleus (round, blue‑grey) - Mitochondria (bean‑shaped, pink) - Lipid droplets (small yellow circles) - Plasma membrane (thin black line) - Extracellular space (outside the cell) Place the following proteins (as text labels) in their correct locations: In the NUCLEUS: RCOR2 (red), MTF1 (red), also MYBL1 (blue) and MATR3 (blue). On MITOCHONDRIA: NOXA (red) and BIM (red) directly on the outer membrane. In the CYTOPLASM: IFIH1 (red), KARS (red), RGS3 (red), GAD1 (red), plus HECW2 (blue), USP38 (blue), PDE9A (blue), UPF0728 (blue), PABPC4 (blue). On a LIPID DROPLET: FABP1 (red). On the PLASMA MEMBRANE: TSPAN9 (red) and RGS3 (red, associated). In EXTRACELLULAR SPACE: LIF (red) and WFIKKN1 (red) as small spheres. In the background, faint grey crossed‑out labels: MYH1, MYH6 (muscle proteins, not endogenous). Add arrows and pathways: - A thick red arrow from NOXA and BIM pointing to the centre of a mitochondrion, labelled "MOMP → cytochrome c release". - A red arrow from IFIH1 to a nearby MAVS‑like symbol, then to a caspase‑8 symbol, then to the mitochondrion (labelled "amplifies MOMP"). - A red dotted arrow from MTF1 and FABP1 pointing to a reactive oxygen species (ROS) icon, then Mehr sehen