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A split-screen scientific illustration shows on-target drug binding to KRAS and off-target binding causing muscle damage.

A split-screen scientific illustration shows on-target drug binding to KRAS and off-target binding causing muscle damage.

A split-screen scientific illustration explaining the failure of drug candidate "compound 12". Left side: a small molecule drug (green) binding perfectly to its intended target protein (KRAS), labeled "on-target effect". Right side: the same drug (red) covalently binding to an unintended protein, labeled "off-target binding", causing a muscle cell below to become damaged and waste away. Simple cartoon style, clean white background, educational diagram with arrows and labels Ver más

#scientific illustration #biology #chemistry

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